טכפידרה - הבית לחולי טרשת נפוצה (ע''ר)

הבית לחולי טרשת נפוצה

טכפידרה

טכפידרה TECHFIDERA DIMETHYL FUMARATE

התווית משרד הבריאות:

טרשת נפוצה (ט.נ) התקפית – הפוגתית. מחלה סוערת, אירוע קליני בודד(CIS). ט.נ – שניונית מתקדמת פעילה.

צורת מתן ומינון

כמוסות במינון מדורג – בשבוע ראשון MG 1X2120 ולאחר מכן 2X1 MG 240

מנגנון פעולה

מנגנון הפעולה מבוסס על הסטה לטובת ייצור תאים נוגדי דלקת מקבוצת 2TH על חשבון תאים דלקתיים מקבוצת תאי ה- 1TH וכך ייצור מופחת של ציטוקינים דלקתיים ועליה ביצור ציטוקינים נוגדי דלקת.

תופעות לוואי

הסמקה, תחושת חום וגרד עור הגוף. בחילות, כאבי בטן, שלשולים, הקאות, ירידה ברמת לימפוציטים. יש לבצע בדיקות דם סדירות, הריון – לאחר ייעוץ רופא.

שימו לב! טרם תחילת כל טיפול יש להתייעץ עם הרופא המטפל לבצע את כל הבדיקות הנדרשות בטרם תחילת הטיפול , ולבצע בדיקות מעקב כפי שנדרש בכל טיפול ועל בסיס המלצות הרופא המטפל.

ההתוויות המופיעות הינן אלו המומלצות ע"י סוכנות המזון והתרופות האמריקאית-FDA . התוויות אלו מקובלות ברוב מדינות העולם. משרד הבריאות הישראלי באמצעות סל הבריאות/סל השירותים משנה מיתווה זה ע"י הכנסת הנחיות נוספות בצורת דרוג התרופות על בסיס פעילות מחלה: קו ראשון, קו שני, קו ראשון- שני, קו שלישי. ההנחיות מכלילות ברובן המכריע את התסמונת הקלינית הבודדה(CIS), בסל אין המלצות לצורת המחלה – שניונית- מתקדמת פעילה(ACTIVE SECONDARY PROGRESSIVE).

שתפו:

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