מייבנקלאד - הבית לחולי טרשת נפוצה (ע''ר)

הבית לחולי טרשת נפוצה

מייבנקלאד

מייבנקלאד MAVENCLAD CLADRIBINE

התווית משרד הבריאות:

טרשת נפוצה (ט.נ) התקפית פעילה מאוד

צורת מתן ומינון

טבליות 10 מ"ג
מינון נקבע בהתאם למשקל גוף. פרוטוקול הטיפול: שנה 1: 4-5 ימים תחילת הטיפול.
2 .לאחר חודש שוב 4-5 ימי טיפול. 3. לאחר שנה שוב 4-5 ימי טיפול בחודש ראשון ובחודש שני. ללא טיפול שנים 3ו-4.

מנגנון פעולה

מנגנון הפעולה מבוסס על הורדת סלקטיבית של הלימפוציטים מקבוצת תאי ה-T ומקבוצת תאי ה-B ויצירה מחודשת של לימפוציטים. (Immune Reconstitution)
בצורה כזאת מוחלשת פעילות המחלה.

תופעות לוואי

רשימה חלקית: ירידה בספירת הלימפוציטים בדם. הרפס זוסטר, פריחה
יש להשלים בדיקות סקר לפני שימוש.
ייעוץ רופא טרם החלטה על הריון .
לרשימה המלאה יש לקרוא את העלון למטופל

שימו לב! טרם תחילת כל טיפול יש להתייעץ עם הרופא המטפל לבצע את כל הבדיקות הנדרשות בטרם תחילת הטיפול , ולבצע בדיקות מעקב כפי שנדרש בכל טיפול ועל בסיס המלצות הרופא המטפל.

התרופה מבוססת רישום EMA . משרד הבריאות הישראלי באמצעות סל הבריאות/סל השירותים משנה מיתווה זה ע"י הכנסת הנחיות נוספות בצורת דרוג התרופות על בסיס פעילות מחלה: קו ראשון, קו שני, קו ראשון- שני, קו שלישי. ההנחיות מכלילות ברובן המכריע את התסמונת הקלינית הבודדה(CIS), בסל אין המלצות לצורת המחלה – שניונית- מתקדמת פעילה(ACTIVE SECONDARY PROGRESSIVE).

שתפו:

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