רביף - הבית לחולי טרשת נפוצה (ע''ר)

הבית לחולי טרשת נפוצה

רביף

רביף INTERFERON BETA-1A

התווית משרד הבריאות:

טרשת נפוצה (ט.נ) התקפית. אירוע קליני בודד. ט.נ- שניונית מתקדמת התקפית.

צורת מתן ומינון

הזרקה תת-עורית של 22/44 MCG 3 פעמים בשבוע.

מנגנון פעולה

עיכוב בהצגת אנטיגנים הסטה של ייצור תאים דלקתיים מסוג 1TH לתאים נוגדי דלקת מסוג 2TH וכך ירידה ברמת הציטוקינים הדלקתיים ועליה ברמת הציטוקינים האנטי- דלקתיים.

תופעות לוואי

רשימה חלקית: כאבי ראש, תופעות דמויות שפעת, תגובה מקומית במקום ההזרקה (אודם או דלקת), שינוי בתפקוד כבד, שינוי בספירות הדם. ניתן להשתמש במהלך הריון ובהנקה. לרשימה המלאה יש לקרוא את העלון למטופל

שימו לב! טרם תחילת כל טיפול יש להתייעץ עם הרופא המטפל לבצע את כל הבדיקות הנדרשות בטרם תחילת הטיפול , ולבצע בדיקות מעקב כפי שנדרש בכל טיפול ועל בסיס המלצות הרופא המטפל.

התרופה מבוססת רישום EMA . משרד הבריאות הישראלי באמצעות סל הבריאות/סל השירותים משנה מיתווה זה ע"י הכנסת הנחיות נוספות בצורת דרוג התרופות על בסיס פעילות מחלה: קו ראשון, קו שני, קו ראשון- שני, קו שלישי. ההנחיות מכלילות ברובן המכריע את התסמונת הקלינית הבודדה(CIS), בסל אין המלצות לצורת המחלה – שניונית- מתקדמת פעילה(ACTIVE SECONDARY PROGRESSIVE).

שתפו:

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